If you run up the project wizard, go into "remove a project" and select "Default" as the project that you wish to remove, then press Finish. This will now remove the default project. Now go into the project wizard and select "Create a new project". Call this project "Default" and then choose the paths you want for methods, data, sequences, and templates. i.e. choose C:\EZChrom Elite\Data for data files etc. and then press finish. You now have a default project that is pointing at the directories that you want.
If this does not answer your question or solve your problem, then please contact us at support@biochrom.co.uk detailing your question or the problem you are experiencing. Please list if relevant the instrument, software and version numbers you are running, and enclose any relevant data files, etc.