Biochrom 30+ Series of Amino Acid Analyzers

Biochrom launches the Biochrom 30+ Series of amino acid analyzers -the gold standard in dedicated amino acid analysis. Clinical laboratories worldwide trust this well documented classical amino acid analysis method based on ion exchange with post column derivitization with Ninhydrin.This allows both qualitative and quantitative analysis of up to 56 amino acids and derivatives, including Argininosuccinic acid, Alloisoleucine and Sulfocysteine.

The Biochrom 30+ Physiological system uses a combination of 5 lithium citrate buffers to achieve a full amino acid profile in less than 90 minutes using the new Accelerated method. 

• Metabolic screening and clinical research on plasma, urine or CSF in Metabolic, Clinical biochemistry and Pedriatric labs in hospitals, contract analysis labs and other clinical institutions
• Clinical research in Universities and veterinary labs.
• QC and composition analysis in bioscience and pharmaceutical companies

Specific applications

• Detection and monitoring of metabolic disease and inborn errors of metabolism (IEM), such as PKU and MSUD and other aminoacidopathies in urine, plasma and CSF.
• Protein and peptide analysis for pharmaceutical applications.
• Food, beverages, plant extracts, fermentation products, culture media, nutraceuticals and infusion fluids

A Dedicated Amino Acid Analysis System

Accurate: Superb separation accurately identifies and quantifies free amino acids, as well as the amino acid composition of proteins and peptides.
Reliable: Minimal matrix interference and near baseline separation helps to reduce ambiguities in interpretation and increase confidence in diagnosis of inborn errors of metabolism. Automated derivatization of amino acids maximizes reproducibility.
Fast: Rapid protocols that increase sample throughput by cutting analysis time.
Economical: The column cleaning and repacking service, gives columns an almost indefinite life and cuts the cost of ownership.
Fully Automated: Total PC control allows 24/7 operations.
Versatile: Wide variety of sample types compatible: Urine, plasma, serum, CSF, amniotic fluid, culture media, tissue extracts, protein hydrolysates from various food and feedstuff samples or synthetic drugs, nutraceuticals, beverages.
Easy to implement: No lengthy method development required as this well characterized system is established worldwide. All customers have their instrument optimised to their application directly from the factory.
Convenient: Interchangeable sample trays allow samples to be prepared in advance and stored refrigerated.
Robust: Advanced fluidics and robust hardware mean easy maintenance for users, backed by the reassurance of Biochrom's dedicated service and support team.
Flexible: Integrated software, choice of different methods to adapt to the user's needs. Automatic sample set-up. Networking and exporting of data.
Compact: Bench top design requiring minimum lab space.

3 full screening methods are available that you can choose according to your business needs:

For a Chromatogram of the accelerated method download the new datasheet below.

Why you need a dedicated instrument for amino acid analysis?
The diagnosis and treatment of various disorders are greatly advanced using a dedicated amino acid analyzer. The difficulty of analyzing amino acids with conventional HPLC systems is mainly due to the complex nature of the samples and the unique chemical properties of the amino acids (ionic compounds with no specific absorption wavelength). A dedicated system is the most reliable solution for consistent and reproducible results. Most of the illnesses caused by inborn errors of metabolism (IEM) can be identified by amino acid analysis of urine, cerebrospinal fluid and blood plasma. Early detection in newborn infants allows necessary treatment to be applied rapidly. Method development is not required on a dedicated AAA as it has been already set up and extensively tested so it can be used routinely 24/7 with little user intervention.
Reliable rapid screening of large numbers of samples for specific amino acids can be performed 24 hours per day using short methods e.g. for PKU and MSUD disorders.
Biochrom has a large number of clinical users worldwide ranging from research labs, children's hospitals and regional centres, to large national reference laboratories.

Biochrom 30+ Physiological Systems

All include PC, cooled Autosampler and  EZChrom Elite. Details of the Biochrom 30+ instrument package

Reagents:

• 80-2118-30  Ultra Ninhydrin Reagent Kit 2L

• 80-2117-77  Ultra Physiological Fluid Chemical Kit*

For Buffers and reagents

	File Description	File Size
	Biochrom 30 Amino Acid Analyzer Clinical/Physiological Brochure Amino acid analysis in clinical and physiological samples. For the detection and monitoring of in born errors of metabolism such as PKU and MSUD.	659 KB